Joshua Kaplan Selected Research

HTI 042

9/2004

Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286).

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Joshua Kaplan Research Topics

Disease

10	Neoplasms (Cancer) 01/2022 - 09/2004
2	Anemia 12/2019 - 05/2011
1	Seizures (Absence Seizure) 01/2023
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2023
1	Hypophosphatemia 02/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Lupus Nephritis 01/2021
1	Infections 01/2021
1	Chronic Renal Insufficiency 12/2019
1	Inflammation (Inflammations) 01/2019
1	Epilepsy (Aura) 01/2019
1	Wounds and Injuries (Trauma) 01/2016
1	Sepsis (Septicemia) 08/2014
1	Critical Illness (Critically Ill) 08/2014
1	Chronic Disease (Chronic Diseases) 05/2011
1	Iron Deficiencies 05/2011
1	Hypoxia (Hypoxemia) 01/2010
1	Glioma (Gliomas) 01/2010
1	Breast Neoplasms (Breast Cancer) 10/2004
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2004

Drug/Important Bio-Agent (IBA)

3	TOR Serine-Threonine KinasesIBA 01/2010 - 08/2009
2	HydrolasesIBA 01/2023 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 02/2010 - 01/2010
2	Proteins (Proteins, Gene)FDA Link 01/2010 - 10/2004
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2010 - 03/2008
2	HTI-286IBA 05/2005 - 10/2004
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2005 - 10/2004
1	Serine (L-Serine)FDA Link 01/2023
1	Gadolinium DTPA (Magnevist)FDA Link 02/2021
1	Phosphates (Orthophosphate)IBA 02/2021
1	GadoliniumIBA 02/2021
1	Calcineurin InhibitorsIBA 01/2021
1	voclosporinIBA 01/2021
1	roxadustatIBA 12/2019
1	EndocannabinoidsIBA 01/2019
1	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2016
1	Prolyl-Hydroxylase InhibitorsIBA 05/2011
1	Erythropoietin FDA Link 05/2011
1	morpholineIBA 02/2010
1	temsirolimus FDA Link 01/2010
1	Phosphotransferases (Kinase)IBA 01/2010
1	Antineoplastic Agents (Antineoplastics)IBA 01/2010
1	MTOR InhibitorsIBA 01/2010
1	Mechanistic Target of Rapamycin Complex 2IBA 01/2010
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2010
1	Sirolimus (Rapamycin)FDA Link 01/2010
1	Bevacizumab (Avastin)FDA Link 01/2010
1	WYE 125132IBA 01/2010
1	hemiasterlinIBA 05/2005
1	Paclitaxel (Taxol)FDA LinkGeneric 05/2005
1	multidrug resistance-associated protein 1IBA 10/2004
1	HTI 042IBA 09/2004

Therapy/Procedure

3	Therapeutics 01/2010 - 08/2009
1	Adrenalectomy 01/2022
1	Length of Stay 01/2022
1	Operative Time 01/2022
1	Gynecologic Surgical Procedures (Gynecologic Surgery) 01/2016
1	Stents 01/2016
1	Continuous Renal Replacement Therapy 08/2014
1	Oral Administration 01/2010
1	Drug Therapy (Chemotherapy) 12/2005